New Orleans. Arrogant, carefree Prince Naveen and hardworking waitress Tiana cross paths. Prince Naveen is transformed into a frog by a conniving voodoo magician. Tiana follows suit when she decides to kiss the amphibian royalty. With the help of a trumpet-playing alligator, a Cajun firefly, and an old blind lady who lives in a boat in a tree, Naveen and Tiana must race to break the spell and fulfill their dreams.

Set in the great city of New Orleans, a beautiful girl named Tiana meets a frog prince who desperately wants to be human again, and a fateful kiss leads them both on a hilarious adventure through the mystical bayous of Louisiana.